Diclofenac and ibuprofen are two of the most widely used analgesics and non-steroidal anti-inflammatory drugs on the market, reporting excellent effects for treating pain and inflammation caused by minor or moderate injuries, small surgical interventions, and even small surgical interventions for other conditions that may cause discomfort. More intense, such as arthritis or calcific tendonitis. Usually, before any pain or discomfort warrants it, the specialist will prescribe one of the two medications. However, many people wonder if diclofenac can be combined with ibuprofen to obtain a more significant analgesic effect. In this FastlyHeal article, we explain whether it is convenient to mix both products.
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Is it convenient to combine both drugs?
When in doubt as to whether diclofenac can be combined with ibuprofen, the answer of the specialists is obvious: the two drugs should not be mixed. Advil can interact with diclofenac or vice versa, producing possible side effects in the patient that can be very annoying.
Since both are non-steroidal anti-inflammatory drugs belonging to the group of NSAIDs, they should not be combined because they have the same effect: reduce inflammation and serve as an analgesic to reduce pain. Together the effect is not potentiated but there is a risk of affecting health. Usually, one of the two is prescribed and can be combined with another group of drugs at the specialist’s discretion.
A much more common combination is diclofenac with paracetamol, which can be prescribed under certain conditions and medical supervision.
What happens if I combine diclofenac with ibuprofen?
Combining diclofenac with ibuprofen can lead to specific, very annoying side effects such as:
- Stomach pain and discomfort.
- Sickness.
- Vomiting
- Ulcers.
- It reduced heart rate.
- Drop-in body temperature
If you have been prescribed diclofenac or ibuprofen to treat pain and inflammation and you consider that their effect is not as expected, it is essential to consult your doctor before stopping a treatment or taking another analgesic of the NSAID type, as this could have significant consequences on Your Health.
This article is merely informative. At FastlyHeal .com, we do not have the power to prescribe medical treatments or make any diagnosis. We invite you to see a doctor in the case of presenting any condition or discomfort.
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
I am a Surgeon with a diploma in comprehensive ultrasound and surgical care residency, an area I am specializing in. During the exercise of my profession, I have realized the need for patients to know the diseases they suffer, and I can tell you that a large part of their complications is due to a lack of information. Being a health web writer allows me to transmit my experience, without borders, to all those readers eager for knowledge, educate them in the prevention of diseases and promote a healthy lifestyle.