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Simethicone: what is it for, dosage, contraindications

by Alivia Nyhan
Published: Last Updated on

It is likely that at some point in your life you have been prescribed activated dimethicone , especially when there is distention in the abdomen due to gases, meteorism, excess air in the intestine, abdominal pain, among others, and they are all sufficient reasons to indicate this potent antiflatulent.

Simethicone is the best known name for this defoamer which is composed of dimethylpolysiloxane and silicon oxide. Its mechanism of action is basically to disperse the gas bubbles and prevent them from forming even more, considerably reducing the surface tension of the bubbles so that they break and are eliminated by flatus or belching.

If you want to know more about this drug, we invite you to continue reading this FastlyHealarticle about Simethicone : what it is for, dosage and contraindications.

Simethicone: what is it

There is no medical severity described before the consultation about flatulence or discomfort caused by excess gas in the gastrointestinal tract. Whatever the cause, dietary modifications make it possible to considerably reduce the annoying source of flatulence.

The intestine contains <200 mL of gas, around 75% of the gases derive from the colonic fermentation of ingested nutrients, according to the Merck Manual. On the other hand, it is common to have flatus between 13 and 21 times a day, which means between 0.5 and 1.5 L, and some people have more or less [1] .

In order to reduce symptoms quickly, antiflatulents were devised , the best known being simethicone. Dimethylpolysiloxane and silicon oxide are the main components of the most widely used antiflatulent in the world, a propellant for the stomach and intestines that is available under different trade names:

  • Aeroflat
  • Lupidon
  • Antifom
  • Evigax
  • Flatoril
  • Espaven
  • Pancreoflate
  • Suxidina

Any of them can be purchased without a prescription, however, its use under the supervision of a doctor is always recommended.

Simethicone: what is it for?

Simethicone fundamentally makes it possible to reduce the surface tension of gas bubbles so that they break, merge into a larger one and are easily eliminated in the form of a burp or flatus.

It has been established in this way that it meets two essential foundations:

  1. Disperse gas bubbles.
  2. Prevents the formation of new bubbles.

In this way, it achieves its basic therapeutic effect: antiflatulent and antifoam. Therefore, we can say that dimethicone is used for the treatment of:

  • Dyspepsia: discomfort that manifests in the stomach after eating food. This includes heartburn, heaviness, flatulence, abdominal pain.
  • Aerocolia : defined as excess air in the colon.
  • Meteorism: medical term that defines the distention of the abdomen due to the accumulation of gases.
  • It can also be indicated prior to medical tests, such as ultrasound or X-ray, where other conditions need to be assessed.

Simeticona: dose

The form of administration of simethicone depends on its pharmacological presentation:

  • Grágeas of 40 mg.
  • 80 mg chewable tablets.
  • 125 mg soft capsules.
  • Suspension drops of 80 mg.

The recommended dose of simethicotine in adults is:

  • 40 mg to 125 mg is administered orally every 8 hours, three times a day after each meal.
  • Maximum daily dose 500 mg / day.

If not dren , should always be administered under pediatric supervision, standard dose ranges in:

  • 2-12 years: 40 mg orally every 6 hours or 10-22 drops before each meal and just before bedtime.
  • Do not exceed the maximum dose of 500 mg / day.
  • <2 years: 20 mg orally every 6 hours or 5-9 drops every 6 hours just before breastfeeding or before each bottle.
  • Do not exceed the maximum dose of 330 mg / day in children.

Simethicone: contraindications, side effects and interactions

The contraindications of simethicone are:

  • Like all drugs, simethicone is contraindicated mainly in cases of hypersensitivity reaction to the component.
  • In case of intestinal obstruction.
  • In case of intestinal perforation.
  • In case of duodenal ulcer.
  • In case of gastrointestinal bleeding.
  • In case of breast cancer being treated with chemotherapy.

Regarding the side effects of simethicone, constipation has eventually been described as the main adverse effect , however, any unfavorable reaction after its use should be seen by the family doctor immediately.

Likewise, there are no drug interactions described in relation to simethicone and other drugs, despite this, it is always recommended to let the doctor know about other drugs that are being taken for other underlying conditions.

The person, in addition, must comply with some recommendations to avoid the production of gases in the gastrointestinal tract, which include:

  • Avoid consuming hot foods.
  • Avoid eating and drinking in a rush.
  • Avoid tobacco.
  • Avoid chewing gum.
  • Avoid drinking glucose beverages.

In the following article, we explain in detail the causes, treatment, and proper diet for intestinal gas .

Simethicone in pregnancy and lactation

Simethicone favorably:

  • It is not absorbed from the gastrointestinal tract.
  • It is not modified by the gastrointestinal flora.
  • It does not interfere with the secretion of gastric juice.
  • It does not interfere with the absorption of other nutrients.
  • It is considered an inert molecule.
  • It is excreted in the feces.

Therefore, simethicone is a safe drug to use in pregnancy and lactation, as it is non-toxic and is not absorbed by the mother or the infant, as described.

It is quite safe to use simethicone in both infants and adults, however, the fundamental recommendation is based on the use of any drug after medical indication, thus avoiding interactions with other drugs and adverse reactions described.

This article is merely informative, at FastlyHeal .com we do not have the power to prescribe medical treatments or make any type of diagnosis. We invite you to see a doctor in the case of presenting any type of condition or discomfort.

If you want to read more articles similar to Simethicone: what it is for, dosage, contraindications , we recommend that you enter our category of Medication and medical tests .

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