Nolotil is a drug whose active substance is magnesium metamizole. It is a drug widely consumed in some regions because it is analgesic, antipyretic and spasmolytic. It is used for almost any type of pain, to lower fever, and to calm or relieve seizures or spasms.
Although it is a reasonably popular medicine in Spain, its sale is prohibited in other countries, such as the United Kingdom, the United States, and Australia. After several studies, it was discovered that the consumption of nolotil causes agranulocytosis. This disease can be fatal, and it affects the bone marrow causing it not to produce enough neutrophils, a type of white blood cell. However, the cases of agranulocytosis generated by the administration of metamizole are not very frequent, and there are between 0.2 and 10 cases per million inhabitants.
For this reason, it is still being marketed in some countries. Although it is essential to consult a doctor to consume any medicine, many people self-medicate. For example, they use metamizole to reduce fever or minor pain without knowing its risks. That is why at FastlyHealwe want you to know the side effects of nolotil.
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Agranulocytosis and thrombocytopenia
Although it is not very common, it is one of the most dangerous side effects of nolotil, that there is a change in the levels of white blood cells in the body, and agranulocytosis appears. It is a pathology in which the bone marrow does not generate the sufficient amount of white blood cells that it produces typically, modifying the values in the blood and becoming fatal in some cases.
Another of the most relevant side effects of nolotil, although it is not common to happen, is that it causes thrombocytopenia. It is a decrease in the amount of circulating platelets in the bloodstream. People with these diseases tend to have a fever quite often as they are prone to infections.
Like almost any other drug, nolotil can cause allergies in some people, even those who have already taken metamizole and have not had any symptoms of an allergic reaction to the drug.
Allergy sufferers may have itchy eyes or skin, skin changes in skin color and texture, hives may appear, lips or sometimes face or tongue swell, and difficulty breathing. Very rarely does an allergy become complicated and lead to anaphylaxis, a different type of allergic reaction that can be fatal. This could cause, among other things, abdominal pain, diarrhea, dizziness, fainting, vomiting, and a racing heartbeat.
Other adverse effects of metamizole
Administration of high doses of metamizole can cause interstitial nephritis in those who already suffer from kidney disease. It is a kidney disorder that causes swelling in the spaces between the kidney tubules, causing the kidneys to malfunction.
Another side effect of nolotil is oliguria, a disease characterized by an abnormal decrease in the volume of urine released in a day. Consumption of the drug metamizole can also cause polyuria, the opposite of oliguria. That is, there will be an abundant excretion of urine. Finally, there is proteinuria, which consists of the presence of proteins in the urine, altering normal levels.
This article is merely informative. At FastlyHeal .com, we do not have the power to prescribe medical treatments or make any diagnosis. We invite you to see a doctor if you present any type of condition or discomfort.
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I am a Surgeon with a diploma in comprehensive ultrasound and surgical care residency, an area I am specializing in. During the exercise of my profession, I have realized the need for patients to know the diseases they suffer, and I can tell you that a large part of their complications is due to a lack of information. Being a health web writer allows me to transmit my experience, without borders, to all those readers eager for knowledge, educate them in the prevention of diseases and promote a healthy lifestyle.