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How to remove histamine from the body

by Alivia Nyhan
Published: Last Updated on

Histamine is present in numerous tissues of the human body: it allows functions as diverse as digestion, circulation, or the proper functioning of the immune system. But what happens when the amount of histamine is high? When the enzyme that degrades it does not work correctly or the allergic symptoms are so great that many histamines are circulating, it is essential to reduce or eliminate it.

If you want to know a little more about what it is about and how to eliminate histamine from the body when its levels are high, we invite you to read this article by FastlyHeal.

What is histamine

Histamine is a product present in all living beings, produced from an amino acid: histidine. Histamine is present in the human body in two ways:

  • Endogenous: The one manufactured in the body, which is the main one.
  • Exogenous: That which is ingested with certain foods.

Histamine is an important molecule, especially the endogenous one since it performs many functions. Here are some of the tasks of histamine :

  • Contraction of smooth (non-voluntary) muscles such as those found in the stomach, intestines, vessels, or bronchi.
  • Production of gastric acid and other body secretions.
  • Regulation of circulation.
  • Critical in the normal functioning of the immune system.
  • Cicatrization.
  • It is the substance that is released in an allergic reaction.
  • Facilitates the transmission of nerve impulses in some nervous system regions (neurotransmitters).

Why do I have high histamine?

We have seen that histamine is present in all living beings and that it is an essential part of their constitution. Still, there are a series of diseases that occur when there is high circulating histamine in the body, such as:

  • Migraine.
  • Allergies
  • Fibromyalgia
  • Excessive tiredness
  • Psoriasis.
  • Arrhythmias, hypo, or hypertension.
  • Irritable bowel
  • Constipation.

CAD deficit

In the above cases, the cause of too much histamine in the blood may be a disease known as DAO deficiency (diamine oxidase), which is the lack of the enzyme that is usually responsible for degrading the histamine that is ingested with food.

Foods that contain biogenic amines are the ones that increase histamine. These are:

  • Red wine.
  • Sausages and sausages.
  • Preserves.
  • Ripened cheeses.

When a person eats these foods and has a DAO deficiency, they can experience some of the diseases that we mentioned previously, having a variety of symptoms such as:

  • Migraine-type headaches.
  • Asthenia.
  • Pain in muscles and joints for no other apparent reason.
  • Skin or respiratory allergies.

Very allergic person

On the other hand, an atopic or very allergic person may also have high levels of histamine because their immune system will be permanently stimulated by those substances that cause an exaggerated reaction, appearing with very varied symptoms such as:

  • Clear nasal or bronchial secretions.
  • Sneezing
  • Itchy eyes and nose.
  • Broncoespasmos.
  • To.
  • Skin dermatitis.

Tips to remove histamine from the body

As we have seen, we must conclude that histamine cannot be eliminated from the body, as it is essential for its proper functioning. Now, when for some reason, the circulating histamine is higher than what the body needs, ways can be found to reduce it through diet.

Avoid foods with histamine

As for foods with histamine, it is very controversial since there is a lot of variation in the amount of histamine from one product to another, from one sample taken in one study to another. But broadly speaking, foods with histamine should be avoided :

  • Foods that contain biogenic amines: red wine, fermented cheeses, pickles, canned bluefish, or sauerkraut.
  • Foods that increase own or endogenous histamine: chocolate, additives from processed products (flavorings, glutamate, benzoate, among others), nitrites, and sulfites.
  • Alcohol: The issue with this type of drink deserves a separate study since it has been seen that it interferes with the normal metabolism of histamine, whether it is a healthy person or one suffering from DAO deficiency and, therefore, its consumption. It makes histamine unable to be eliminated, and it is kept longer and in more significant amounts than it should. After drinking it, the face may become red, feel hot, or have the symptoms of a “hangover.” Therefore, anyone who wants to lower their histamine levels should avoid alcohol consumption.

On the other hand, the consumption of certain foods that cause inflammation in the body should also be limited or replaced by healthier foods. Gluten and dairy are two products that complicate the situation, especially for allergy sufferers. An excellent way to keep the body cleaner is to avoid them.

To know if this will help you treat the symptoms of high histamine in the body, do a test:

  • Avoid these foods with histamine for about three weeks.
  • Reincorporate them one by one.
  • See the evolution.

A diet rich in fruits and vegetables, incredibly raw seeds, and sprouts can help you regain your lost balance.

If you want to know all the foods that contain histamine, we recommend Foods with histamine – Complete list!


Finally, another way to reduce histamine that we must mention is antihistamines. This type of drug takes the place that histamine wants to occupy in the receptors in the tissues, so although it certainly does not eliminate it from the body, it does not allow it to cause the symptoms that appear when there is too much histamine or high histamine.

These are the main benefits of antihistamines:

  • Eliminate allergic symptoms.
  • They produce less gastric acid.
  • Migraine symptoms decrease.

It is a different drug that works for another receptor for each of these. The correct indication of the antihistamine will be according to the symptoms suffered by the person and the doctor’s diagnosis.

This article is merely informative. At FastlyHeal .com, we do not have the power to prescribe medical treatments or make any diagnosis. We invite you to see a doctor if you present any type of condition or discomfort.

If you want to read more articles similar to How to remove histamine from the body, we recommend that you enter our category of Medication and medical tests.

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