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High sideremia: causes

by Alivia Nyhan
Published: Last Updated on

Until we do a blood test and the doctor names this word for us, it is likely that we have never heard the name siderermia in our lives. Also known as serum iron, sideremia is the amount of iron in our blood serum. It is not a disease or a pathology as its name could lead us to anticipate, but it is something ordinary and necessary for the body. However, it may be due to different complications that we will explain later when its values ​​are altered, either due to low serum iron or high serum iron.

The analysis to know the blood values ​​of the sideremia is usually carried out to diagnose anemia or other diseases of hematological origin, so it is essential to know its origin to treat it. In the following FastlyHeal article, we will explain everything you need to know about high sideremia: causes, the values ​​you should have, and what to do to treat it.

High sideremia: meaning

We understand by sideremia the serum iron present in the blood serum. Blood serum is a yellow liquid that makes up Blood that resembles plasma, but unlike plasma, it does not contain fibrinogen, the proteins that help clot. This yellow tone of the blood serum can be observed after blood clotting, for example, in a wound.

If the serum iron concentration is the serum iron concentration, the high serum iron will be when this concentration presents higher values than it should, which may be due to different conditions that we will see below.

It is convenient to clarify that serum iron or sideremia is not the same as ferritin. This clarifies to us the capacity of fixation in the iron that is transported by the transferrin. If you want to know more about ferritin and high ferritin, you can do so in the following article.

Sideraemia: normal values

As a general rule, typical values ​​for sideremia should be between 50 mg / dL and 150 mg / dL. However, factors such as gender, age, or general health can cause what is understood by normality. For example, it is normal for the serum iron concentration to be higher than in women in men.

Usually, we understand high sideremia when the values ​​exceed 150 mg / dL, a medical condition known as hypersideremia. On the other hand, we consider the serum iron concentration below 30 ug / dL to be hypodermic.

High sideremia: causes

High sideremia, high serum iron, or hypersideraemia can be due to many different conditions, although most are related to blood disorders. Here we explain what the leading causes of high sideremia are:

hemolytic anemia

Hemolytic anemia is a blood disorder that occurs when there are not enough healthy red blood cells in our bloodstream. Red blood cells usually remain active for 120 days, but they can be destroyed much earlier than normal when someone has hemolytic anemia. Considering that the red blood cells are responsible for carrying oxygen to all the body’s tissues, it can become a severe condition.

The cause of this condition is the inability of the bone marrow to replace the red blood cells that are destroyed. However, we find some genetic defect, infection, or intoxication at its origin, either by drugs or some other product. If you want to know more about this condition, we invite you to read about hemolytic anemia: causes, symptoms, and treatment.

Pernicious anemia

Like the previous one, pernicious anemia causes that there are not enough red blood cells in the bloodstream, but unlike the previous one, it is caused by the difficulty or inability of the intestines to be able to absorb vitamin B12, a vital element so that blood cells can be produced.

Autoimmune diseases, gastritis, or damage to the stomach lining can lead to low red blood cells and high blood sugar. Find out all about pernicious anemia in the following article.


This is a blood disorder that has a hereditary origin, and that manifests itself with an unbalanced production of hemoglobin. Since hemoglobin is the substance that carries oxygen through red blood cells, this alteration destroys these cells and causes hemolytic anemia. This article explains more about the causes, types, and symptoms of thalassemias.


Hemochromatosis is a condition that directly causes high blood pressure. It is generally due to a genetic alteration that causes the body to absorb too much of this mineral and concentrate it in the pancreas and liver. However, it can also be caused by excessive alcohol consumption, suffering from thalassemias, or anemia. Find out more about hemochromatosis in this article.


Jaundice is not a disease but is one more symptom of different conditions that can affect the body, especially the liver. Jaundice is the yellowish tone that takes on the skin of those with an increase in bilirubin caused by the aging of the red blood cells. Jaundice results from other diseases, in this case, because of any infection in the liver.

This article is merely informative. At FastlyHeal .com, we do not have the power to prescribe medical treatments or make any diagnosis. We invite you to see a doctor if you present any condition or discomfort.

If you want to read more articles similar to High sideraemia: causes, we recommend that you enter our category of Blood, heart, and circulation.

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