Urbason (methylprednisolone) is a drug belonging to the group of corticosteroids, which act at the cellular level to reduce the production of substances that cause inflammation or allergy . Thanks to its rapid effect, this medicine, specifically its powder and solvent for injected solution, is especially indicated in severe cases that require immediate acute treatment, on the other hand, its tablet form is useful in long-term treatments. In the following FastlyHealarticle, we explain the uses, indications and side effects of Urbasol so that you are adequately informed during treatment.
What is Urbason for
The methylprednisolone works by inhibiting the expression of inflammation and the formation of arachidonic acid. This drug is useful to treat the following pathologies:
- Severe asthmatic attacks.
- Serious allergic reactions and clinical situations that endanger the life of the patient, such as angioedema, that is, hives with swelling of the feet, hands, throat, lips and respiratory tract, or laryngeal edema causing swelling in the throat due to fluid accumulation.
- Rheumatic diseases, such as arthritis, gouty arthritis, ankylosing spondylitis.
- Systemic lupus erythematosus.
- Crohn’s disease .
- Liver diseases
- Nephrotic syndrome .
- Acquired hemolytic anemia and idiopathic thromocytopenic purpura .
- Inflammatory eye diseases.
- In accidental poisonings, such as insect or snake bites, to prevent anaphylactic shock.
- Cerebral edema , that is, swelling of the brain due to fluid accumulation and spinal injuries.
- Addison’s crisis (disorder of the adrenal glands located above the kidneys) and shock secondary to adrenocortical insufficiency.
- Acute flare-ups of multiple sclerosis .
- As an adjuvant in chemotherapy.
- Treatment of acute organ transplant rejection.
How to take Urbason
Once the Urbason indications are known, to take it correctly it is essential to follow the doctor’s instructions at all times, since the dose and duration of treatment will be established according to the health problem that each patient presents.
Urbason 40 mg injection: dose
In general, it is advisable to take 20 to 40 mg in adults and 8 to 16 mg per day in child patients. When the condition is severe and the half hour of application has passed, the desired improvement has not been achieved, the injections can be repeated until reaching the amount of 80 mg, which is the maximum recommended dose.
Depending on the severity of the patient, the injections may be applied at intervals between one and another that can range from 30 minutes to 24 hours.
Only in those cases in which the patient’s life is in danger, it is advisable to start treatment by applying single doses of 250 to 1000 mg in adults and 4 to 20 mg / kg of body weight in children.
Urbason 40 mg tablets: dose
Generally, the starting dose is 12 to 80 mg per day in adult patients and 0.8 to 1.5 mg per kg of body weight in children. Regarding the maintenance dose, they are 4 to 8 mg in adults and 2 to 4 mg in children.
Urbason tablets should be swallowed without chewing with about 1/2 glass of water, during or immediately after a meal.
It is advisable to take the total daily dose in the morning and when the maintenance dose has been established, the dose corresponding to 2 days should be taken on alternate days and also in the morning as a single dose.
Urbason side effects
However, Urbason can produce several adverse effects that are important to be aware of despite the fact that they do not occur in all patients. They can be the following:
- Endocrine disorders.
- Cardiovascular disorders
- Skin disorders
- Blood and lymphatic system disorders.
- Musculoskeletal and connective tissue disorders.
- Gastrointestinal disorders.
- Hepatobiliary disorders.
- Eye disorders
- Immune disorders.
- Nervous disorders
- Psychiatric disorders.
We will explain these disorders in more detail below.
Urbason can cause abnormal fat distribution, obesity, increased blood sugar levels, changes in blood fat levels, missed menstrual periods, and hair growth.
Less frequently, it can cause impotence, adrenal cortex problems, growth retardation in children, increased protein metabolism, elevated urea levels and, in very rare cases, reversible accumulation of fat in the epidural or epidural canal. in the thoracic cavity.
This drug can also cause sodium and water retention and increased elimination of potassium. In patients with heart failure it can increase lung congestion and develop hypertension .
On the other hand, it can also lead to allergic inflammation of the blood vessels, increased pressure in the skull with inflammation of the optic nerve, arrhythmias and cardiac arrest.
Skin and subcutaneous tissue disorders
Frequently, it can trigger skin changes such as atrophy, stretch marks, acne or small spots and, in more rare cases, skin rashes.
It can also cause shock, especially in patients with bronchial asthma or those who have undergone a kidney transplant.
Blood and lymphatic system disorders
Another side effect of Urbason that can occur after taking the drug is slow wound healing, an increase in white blood cells at the beginning of treatment and an increase in the number of platelets, with the risk of thrombosis.
Musculoskeletal and connective tissue disorders
Urbason can cause osteoporosis and lead, in severe cases, to fractures, muscle weakness, severe muscle disease from co-administration of non-depolarizing muscle relaxants and, more rarely, death of bone tissue in the head of the femur or humerus and tendon rupture in people with previous injuries, diabetes or high levels of uric acid in the body.
Other side effects of Urbason
On lesser occasions, the administration of this medicine can cause side effects such as:
- Ulcers of the stomach or duodenum, and if peritonitis, pancreatitis or abdominal discomfort is perforated.
- Lesions in the eyes such as a cloudy lens, increased pressure in the eyes, cataracts, glaucoma or chorioretinopathy.
- Decreased body defenses with increased risk of infection.
- Development or worsening of psychiatric problems that the patient had before starting treatment.
- Atrophy of the skin when the drug is injected into fatty tissue.
Non-progressive withdrawal of Urbason after long treatment could also cause muscle and joint pain, breathing problems, anorexia, nausea and vomiting, fever, low blood pressure and low blood sugar. For this reason, it is important to reduce the doses little by little and only when the doctor recommends it, always following the suggestions of the specialist.
This article is merely informative, at FastlyHeal .com we do not have the power to prescribe medical treatments or make any type of diagnosis. We invite you to see a doctor in the case of presenting any type of condition or discomfort.
If you want to read more articles similar to Urbason Side Effects , we recommend that you enter our Medication and Medical Tests category .
I am a Surgeon with a diploma in comprehensive ultrasound and surgical care residency, an area I am specializing in. During the exercise of my profession, I have realized the need for patients to know the diseases they suffer, and I can tell you that a large part of their complications is due to a lack of information. Being a health web writer allows me to transmit my experience, without borders, to all those readers eager for knowledge, educate them in the prevention of diseases and promote a healthy lifestyle.