Home Medication and medical testsAnti-inflammatories Nimesulide: what it is for, dosage and side effects

Nimesulide: what it is for, dosage and side effects

by Alivia Nyhan
Published: Last Updated on

Analgesics are one of the most widely used drugs in all the world’s countries; among them, the most frequently used are what we know as NSAIDs: non-steroidal anti-inflammatory analgesics. Perhaps the best known of this family of painkillers is ibuprofen, diclofenac, ketorolac, and naproxen, among others. Still, it is a group of extremely large painkillers which share specific characteristics, such as their side effects at the stomach level.

Due to this, it is necessary to always have an alternative on hand for people who suffer from gastric conditions and need to relieve any pain. In this FastlyHealarticle, we will talk about Nimesulide: what it is for, its dosage, and its side effects, since it is a member of a subgroup of analgesics that have a lower capacity to cause gastric damage.

What is Nimesulide: composition

Nimesulide is a drug with analgesic and antipyretic action, which belongs to the family of non-steroidal anti-inflammatory painkillers (NSAIDs), within a particular group of these known as selective COX-2 inhibitors, which gives it the characteristic to cause less gastrointestinal damage, an adverse effect produced by practically all NSAIDs, while retaining its analgesic and anti-inflammatory capacity.

Indications of nimesulide

The development of Nimesulide and other COX-2 selective analgesics was inspired by the need to provide pain relief in people who are at risk for gastric diseases such as gastric ulcers and in those who are on anticoagulants and therefore, Therefore, they cannot take the more common pain relievers such as ibuprofen or diclofenac due to the risk of significant side effects such as stomach bleeding or increased risk of bleeding.

Due to how insulin works, in these patients, there is a much lower risk of causing these side effects since it does not interact with the body in the same way as conventional painkillers in terms of these effects. Still, it does in terms of analgesia, offering similar pain relief.

The cases in which the use of Nimesulide is usually indicated are in which there is acute pain or inflammation, the most common being the following:

  • Rheumatoid arthritis
  • Osteoarthritis
  • Menstrual pain
  • Gynecological disorders
  • Sprains, strains, and fractures
  • Bursitis
  • Surgical interventions
  • Dental pain

Nimesulide: dosis

Nimesulide comes as tablets or tablets of 10 or 20 units of 100 milligrams each.

The number of milligrams consumed in a day and the intervals between them will be indicated by your doctor in your particular case. However, most treatments require a dose of 100 mg every 12 hours, which can be increased to 200 mg every 12 hours depending on the symptoms, although for most cases, it is recommended not to exceed 200 mg per day. The consumption of Nimesulide is recommended after eating.

Contraindications of nimesulide

Nimesulide consumption should be avoided by people who have any of the following conditions:

  • Patients with allergy or hypersensitivity to non-steroidal anti-inflammatory drugs: Although NSAIDs have different components, there is always the risk of a cross response. It is also essential to avoid taking other NSAIDs as much as possible during nimesulide therapy.
  • Active gastric ulcer: Although in patients at risk of gastric ulcers, Nimesulide can be consumed without causing harm, patients with a gastric ulcer or those who have suffered from one are at risk of stomach bleeding.
  • Liver damage or severe kidney damage: Consumption of Nimesulide can lead to impaired kidney function. Similarly, the liver is at risk of injury with short exposure in people who have liver conditions or who use the drug together with other medications with effects on the liver or with alcohol consumption.
  • Heart conditions: The doctor should be consulted about the consumption of Nimesulide by people who have suffered from angina pectoris, heart attacks or heart failure, and pulmonary hypertension since there is a risk of aggravating the condition.
  • Last trimester of pregnancy: Like the rest of the NSAIDs, there is a risk that Nimesulide causes premature closure of the structure known as the ductus arteriosus if consumed during the third trimester of pregnancy, which has severe consequences for the baby.
  • Lactation: Its consumption should be avoided at this stage since it is unknown whether Nimesulide is excreted in human milk.

Nimesulide: side effects

The side effects of consuming Nimesulide depend a lot on the dose that has been taken, so they can be reduced if the amount consumed is reduced. Due to its effect on the liver, consumption for short periods and periodic evaluation of liver function are recommended for those who need treatment with Nimesulide for a long time. The most common side effects include the following:

  • Diarrhea
  • Sickness
  • He retched
  • Dizziness
  • Edema
  • Sweating
  • Itch
  • Flatulence
  • Constipation
  • Hypertension

This article is merely informative, at FastlyHeal .com we do not have the power to prescribe medical treatments or make any type of diagnosis. We invite you to see a doctor in the case of presenting any type of condition or discomfort.

If you want to read more articles similar to Nimesulide: what it is for, dosage, and side effects, we recommend that you enter our category of Medication and medical tests .

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